Avalo Therapeutics
AVTX on Nasdaq. Avalo Therapeutics develops medicines for patients with inflammatory diseases. Market value $783m.
Price checks use the past 12 months to June 2026. Some use the latest annual report instead, as marked. Quality checks use five annual reports, the latest for the year to December 2025.
We can't read total debt from the filing, so debt is left out.
Cash flow or capital spending isn't reported, so free cash flow is unknown.
Should I look at this?
Not a fit for our list right now
Why it could be worth it
Nothing stands out yet.
See Health care stocks that passed both tests
This is not advice. Check the numbers below.
We could not compute this from the filings.
The filings do not give us enough to work this out.
The filings do not give us enough to work this out.
Quality score: 20 of 100. Price score: 16 of 100. Our list needs 70 on quality and 60 on price.
$14.60 a share, 17% above its 1-year low
Over the past year the price has ranged from $12.51 to $24.27.
Pays no dividend
Prices from Monday’s close (5 October).
Five years of cash, in billions
| Revenue | |||||
| Revenue | $5m | $18m | $2m | $441,000 | $59,000 |
| Operating margin | |||||
| Operating margin | -1521.6% | -207.4% | -1421.6% | -15535.6% | -123601.7% |
| Debt to equity | |||||
| Debt to equity | n/a | n/a | n/a | n/a | n/a |
| Shares outstanding | |||||
| Shares outstanding | 0.01bn | 0.19bn | 0.01bn | 0.02bn | 0.05bn |
Health checks
- Free cash flow positive0 of 4 years
- Accounting looks honest (Beneish)Not enough data
- Financial strength (Piotroski)1 of 7 checks we could run
- Profit backed by cash (accruals)No
- DebtUnknown
- Revenue growth, five yearsShrinking, 61.2% a year
- Buying back its own sharesNo, 470% more shares since 2021
The quarter to June 2026
How the business did, compared with the same quarter a year earlier.
- A loss of $36 million, compared with a loss of $21 million a year ago.
- 303% more shares than a year ago. Each share owns a bit less of the company.
| Quarter to | Amount |
|---|---|
| September 2024 | $23m |
| December 2024 | -$35m |
| March 2025 | -$13m |
| June 2025 | -$21m |
| September 2025 | -$31m |
| December 2025 | -$14m |
| March 2026 | -$20m |
| June 2026 | -$36m |
From the company's quarterly reports to the SEC.
Dates
- Next results (estimated)
- n/a
- Last annual report (10-K)
- 23 March 2026
- Next quarterly (estimated, 10-Q)
- 5 November 2026
Who owns it
None of the long-term investors we follow own it. 126 funds in all.
Largest holders overall
- FMR$94mAdded
- BlackRock$81mAdded
- Nantahala Capital Management$69mAdded
- Deep Track Capital, LP$67mNew
- Caligan Partners LP$58mAdded
- TCG Crossover Management$56mAdded
- Affinity Asset Advisors$54mAdded
- State Street$53mAdded
- Farallon Capital Management, L.L.C.$46mAdded
- Point72 Asset Management, L.P.$44mAdded
From 13F filings for the quarter ended 30 June 2026.
Big holders and activists
19 investors own more than 5%.
- FMR LLCPassive investorat least 10.8%+1.1 pts(filed with 1 related holder)Since 31 July 2026
- Commodore Capital LPPassive investorat least 9.9%(filed with 3 related holders)Since 11 June 2026
- TCG Crossover GP II, LLCPassive investorat least 7.9%(filed with 2 related holders)Since 5 May 2026
- Affinity Healthcare Fund, LPPassive investor7.6%+2.4 ptsSince 30 September 2025
- Deep Track Capital, LPPassive investorat least 6.9%+1.1 pts(filed with 2 related holders)Since 30 June 2026
- BlackRock, Inc.Passive investor6.5%Since 30 June 2026
- RA Capital Management, L.P.Passive investorat least 6.3%−3.6 pts(filed with 3 related holders)Since 30 June 2026
- OrbiMed Capital GP IX LLCPassive investor6.0%Since 30 June 2025
- Caligan Partners LPPassive investorat least 5.9%−1.3 pts(filed with 1 related holder)Since 30 June 2026
- Affinity Asset Advisors, LLCPassive investorat least 5.5%0.0 pts(filed with 1 related holder)Since 30 June 2026
- STATE STREET CORPORATIONPassive investor5.5%Since 30 June 2026
- BVF PARTNERS L P/ILPassive investorat least 5.3%−4.7 pts(filed with 9 related holders)Since 30 June 2026
- Point72 Asset Management, L.P.Passive investorat least 5.2%+1.7 pts(filed with 2 related holders)Since 22 May 2026
- Avoro Capital Advisors LLCPassive investorat least 4.4%−1.3 pts(filed with 1 related holder)Since 30 June 2026
- Ikarian Capital, LLCPassive investorat least 3.8%−6.2 pts(filed with 1 related holder)Since 30 September 2025
- Nantahala Capital Management, LLCPassive investorat least 3.5%−5.8 pts(filed with 2 related holders)Since 30 June 2026
- Logos Global Management LPPassive investorat least 3.2%−2.4 pts(filed with 4 related holders)Since 31 March 2026
- SilverArc Capital Management, LLCPassive investorat least 2.8%−2.6 pts(filed with 1 related holder)Since 31 December 2025
- Balyasny Asset Management L.P.Passive investorat least 2.4%−3.8 pts(filed with 4 related holders)Since 31 December 2025
- The Vanguard GroupPassive investorSold down below 5%Since 31 December 2025
- Patrick J. CrutcherPassive investorSold down below 5%Since 6 August 2025
- OrbiMed Advisors LLCPassive investorSold down below 5%Since 31 March 2026
- T. Rowe Price Investment Management, Inc.Passive investorSold down below 5%Since 30 June 2026
- Millennium Management LLCPassive investorSold down below 5%Since 30 June 2026
| Holder | Stake | Since | |
|---|---|---|---|
FMR LLC Passive investor | at least 10.8%+1.1 pts (filed with 1 related holder) | 31 July 2026 | |
Commodore Capital LP Passive investor | at least 9.9% (filed with 3 related holders) | 11 June 2026 | |
TCG Crossover GP II, LLC Passive investor | at least 7.9% (filed with 2 related holders) | 5 May 2026 | |
Affinity Healthcare Fund, LP Passive investor | 7.6%+2.4 pts | 30 September 2025 | |
Deep Track Capital, LP Passive investor | at least 6.9%+1.1 pts (filed with 2 related holders) | 30 June 2026 | |
BlackRock, Inc. Passive investor | 6.5% | 30 June 2026 | |
RA Capital Management, L.P. Passive investor | at least 6.3%−3.6 pts (filed with 3 related holders) | 30 June 2026 | |
OrbiMed Capital GP IX LLC Passive investor | 6.0% | 30 June 2025 | |
Caligan Partners LP Passive investor | at least 5.9%−1.3 pts (filed with 1 related holder) | 30 June 2026 | |
Affinity Asset Advisors, LLC Passive investor | at least 5.5%0.0 pts (filed with 1 related holder) | 30 June 2026 | |
STATE STREET CORPORATION Passive investor | 5.5% | 30 June 2026 | |
BVF PARTNERS L P/IL Passive investor | at least 5.3%−4.7 pts (filed with 9 related holders) | 30 June 2026 | |
Point72 Asset Management, L.P. Passive investor | at least 5.2%+1.7 pts (filed with 2 related holders) | 22 May 2026 | |
Avoro Capital Advisors LLC Passive investor | at least 4.4%−1.3 pts (filed with 1 related holder) | 30 June 2026 | |
Ikarian Capital, LLC Passive investor | at least 3.8%−6.2 pts (filed with 1 related holder) | 30 September 2025 | |
Nantahala Capital Management, LLC Passive investor | at least 3.5%−5.8 pts (filed with 2 related holders) | 30 June 2026 | |
Logos Global Management LP Passive investor | at least 3.2%−2.4 pts (filed with 4 related holders) | 31 March 2026 | |
SilverArc Capital Management, LLC Passive investor | at least 2.8%−2.6 pts (filed with 1 related holder) | 31 December 2025 | |
Balyasny Asset Management L.P. Passive investor | at least 2.4%−3.8 pts (filed with 4 related holders) | 31 December 2025 | |
The Vanguard Group Passive investor | Sold down below 5% | 31 December 2025 | |
Patrick J. Crutcher Passive investor | Sold down below 5% | 6 August 2025 | |
OrbiMed Advisors LLC Passive investor | Sold down below 5% | 31 March 2026 | |
T. Rowe Price Investment Management, Inc. Passive investor | Sold down below 5% | 30 June 2026 | |
Millennium Management LLC Passive investor | Sold down below 5% | 30 June 2026 |
From Schedule 13D and 13G filings: anyone owning more than 5% must file one.
What insiders did
No insider bought shares on the open market in the last 12 months. 6 sold $9m, $8m of it under preset trading plans.
- Sullivan Christopher RyanChief Financial OfficerSoldunder a preset trading plan
- Date
- 16 September 2026
- Shares
- 12,394
- Price
- $16.33
- Value
- $202,437
- Sullivan Christopher RyanChief Financial OfficerSoldunder a preset trading plan
- Date
- 10 September 2026
- Shares
- 10,185
- Price
- $17.62
- Value
- $179,457
- Doyle MittieChief Medical OfficerSoldunder a preset trading plan
- Date
- 28 August 2026
- Shares
- 679
- Price
- $20.00
- Value
- $13,580
- Sullivan Christopher RyanChief Financial OfficerSoldunder a preset trading plan
- Date
- 18 August 2026
- Shares
- 31,031
- Price
- $20.05
- Value
- $622,324
- Doyle MittieChief Medical OfficerSoldunder a preset trading plan
- Date
- 17 August 2026
- Shares
- 1,000
- Price
- $20.00
- Value
- $20,000
- Sullivan Christopher RyanChief Financial OfficerSoldunder a preset trading plan
- Date
- 17 August 2026
- Shares
- 41,694
- Price
- $19.86
- Value
- $828,096
- Riley JenniferChief Strategy OfficerSold
- Date
- 11 August 2026
- Shares
- 2,655
- Price
- $19.59
- Value
- $52,012
- Doyle MittieChief Medical OfficerSoldunder a preset trading plan
- Date
- 10 August 2026
- Shares
- 679
- Price
- $20.00
- Value
- $13,580
- Doyle MittieChief Medical OfficerSoldunder a preset trading plan
- Date
- 27 July 2026
- Shares
- 1,000
- Price
- $20.00
- Value
- $20,000
- Doyle MittieChief Medical OfficerSoldunder a preset trading plan
- Date
- 30 June 2026
- Shares
- 4,654
- Price
- $20.00
- Value
- $93,080
| Date | Who | Did | Shares | Price | Value |
|---|---|---|---|---|---|
| 16 September 2026 | Sullivan Christopher Ryan Chief Financial Officer | Sold under a preset trading plan | 12,394 | $16.33 | $202,437 |
| 10 September 2026 | Sullivan Christopher Ryan Chief Financial Officer | Sold under a preset trading plan | 10,185 | $17.62 | $179,457 |
| 28 August 2026 | Doyle Mittie Chief Medical Officer | Sold under a preset trading plan | 679 | $20.00 | $13,580 |
| 18 August 2026 | Sullivan Christopher Ryan Chief Financial Officer | Sold under a preset trading plan | 31,031 | $20.05 | $622,324 |
| 17 August 2026 | Doyle Mittie Chief Medical Officer | Sold under a preset trading plan | 1,000 | $20.00 | $20,000 |
| 17 August 2026 | Sullivan Christopher Ryan Chief Financial Officer | Sold under a preset trading plan | 41,694 | $19.86 | $828,096 |
| 11 August 2026 | Riley Jennifer Chief Strategy Officer | Sold | 2,655 | $19.59 | $52,012 |
| 10 August 2026 | Doyle Mittie Chief Medical Officer | Sold under a preset trading plan | 679 | $20.00 | $13,580 |
| 27 July 2026 | Doyle Mittie Chief Medical Officer | Sold under a preset trading plan | 1,000 | $20.00 | $20,000 |
| 30 June 2026 | Doyle Mittie Chief Medical Officer | Sold under a preset trading plan | 4,654 | $20.00 | $93,080 |
From Form 4 filings: insiders must report trades in their own company's shares within two days.
Warning signs in its filings
Problems the company itself reported to the SEC, in its own words.
None of the warning signs we check for were found.
We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.
We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 23 Mar 2026, plus the 10-Q filed 6 Aug 2026 and 10 later 8-Ks.
A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.
What could go wrong
- Sales have shrunk: 61.2% a year.
Whether the price already reflects the risks is what the deep dive is for.
The deep dive
Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.
- What the business is worth, as a range, and the margin of safety at today’s price
- Prices to start buying, buy, and buy hard
- The three things that would make this a mistake
- Every number footnoted to the filing it came from
Your first deep dive is free.
Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.