Caris Life Sciences

CAI on Nasdaq. Caris Life Sciences sells molecular cancer tests to hospitals, doctors, and drugmakers. Market value $8.6bn.

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Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

Should I look at this?

Look carefully before going further

Read the warning sign in its own filings

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
1.6%low

For every $100 of what the whole company costs, it produced $1.60 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
47.9×full

You pay 47.9 years of operating profit for the business. The average large US company costs around 18.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: not known. Price score: 16 of 100. Our list needs 70 on quality and 60 on price.

$27.45 a share, 93% above its 1-year low

Over the past year the price has ranged from $14.19 to $33.65.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

0.1
0.1
202512 monthsto Jun '26

Spare cash swings from quarter to quarter here: $124 million in the past 12 months, $67 million in the year to December 2025.

Revenue
$812m
Operating margin
5.6%
Debt to equity
0.66
Shares outstanding
0.28bn

Health checks

  • Free cash flow positive1 of 1 years
  • Accounting looks honest (Beneish)Not enough data
  • Financial strength (Piotroski)Not enough data
  • Profit backed by cash (accruals)Not enough data
  • Debt0.66× equity
  • Revenue growth, five yearsUnknown
  • Buying back its own sharesRoughly flat

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • Sales: $264 million last quarter, up 45% on a year ago.
  • A loss of $637,000, compared with a loss of $72 million a year ago.
  • 336% more shares than a year ago. Each share owns a bit less of the company.
Sales by quarter
Sales by quarter
Quarter toAmount
June 2025$181m
September 2025$217m
December 2025$293m
March 2026$216m
June 2026$264m
Profit by quarter
Profit by quarter
Quarter toAmount
June 2025-$72m
September 2025$24m
December 2025$82m
March 2026-$510,000
June 2026-$637,000

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
3 March 2026
Next quarterly (estimated, 10-Q)
4 November 2026

Who owns it

1 long-term investor we follow owns it, unchanged from 1 last quarter. 246 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

6 investors own more than 5%.

  • David D. Halbert
    Passive investor
    at least 44.1%
    (filed with 1 related holder)
    Since 30 June 2025
  • FMR LLC
    Passive investor
    at least 10.8%+5.8 pts
    (filed with 1 related holder)
    Since 31 March 2026
  • J H Whitney VI LP
    Passive investor
    7.3%
    Since 30 June 2025
  • J H Whitney VI L P
    Passive investor
    at least 4.0%−2.5 pts
    (filed with 3 related holders)
    Since 30 June 2026
  • Alan Waxman
    Passive investor
    at least 2.6%−2.5 pts
    (filed with 1 related holder)
    Since 30 June 2026
  • Millennium Management LLC
    Passive investor
    at least 1.3%
    (filed with 3 related holders)
    Since 17 June 2025

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

In the last 12 months, 4 insiders bought $2m of shares on the open market. 4 sold $29m, $2m of it under preset trading plans.

  • Denton John Russel
    See Remarks
    Sold
    Date
    22 September 2026
    Shares
    7,500
    Price
    $31.82
    Value
    $238,626
  • Brille Brian J
    See Remarks, Director
    Sold
    Date
    17 September 2026
    Shares
    400,000
    Price
    $30.33
    Value
    $12m
  • Spetzler David Baxley
    President
    Sold
    Date
    4 September 2026
    Shares
    119,212
    Price
    $24.76
    Value
    $3m
  • Spetzler David Baxley
    President
    Sold
    Date
    3 September 2026
    Shares
    478,000
    Price
    $24.86
    Value
    $12m
  • HALBERT JON
    Director
    Bought
    Date
    15 May 2026
    Shares
    68,000
    Price
    $14.56
    Value
    $990,080
  • Vacirca Jeff L
    Director
    Bought
    Date
    11 May 2026
    Shares
    31,050
    Price
    $16.15
    Value
    $501,458
  • Power Luke Thomas
    See Remarks
    Sold
    under a preset trading plan
    Date
    11 December 2025
    Shares
    62,250
    Price
    $26.57
    Value
    $2m
  • Spetzler David Baxley
    President
    Bought
    Date
    7 November 2025
    Shares
    400
    Price
    $23.85
    Value
    $9,540
  • Denton John Russel
    See Remarks
    Bought
    Date
    7 November 2025
    Shares
    4,184
    Price
    $24.09
    Value
    $100,793

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

1 serious warning sign in Caris Life Sciences’ filings.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 3 Mar 2026, plus the 10-Q filed 5 Aug 2026 and 5 later 8-Ks.

  • Weak checks on its own accounts

    Serious

    The company said its checks on its own accounts did not work at the end of its latest quarter. Mistakes could slip into the numbers.

    “Based on such evaluation, our principal executive officer and principal financial officer have concluded that these disclosure controls and procedures were not effective at the reasonable assurance level as of June 30, 2026 due to the previously reported material weakness in our internal control over financial reporting pertaining to a lack of sufficient qualified accounting resources, including those necessary to account for and disclose accounting transactions that require complex calculations or thorough evaluation of the accounting literature.”
    Show the full paragraph
    Our management, with the participation of our principal executive officer and principal financial officer, has evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended), as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on such evaluation, our principal executive officer and principal financial officer have concluded that these disclosure controls and procedures were not effective at the reasonable assurance level as of June 30, 2026 due to the previously reported material weakness in our internal control over financial reporting pertaining to a lack of sufficient qualified accounting resources, including those necessary to account for and disclose accounting transactions that require complex calculations or thorough evaluation of the accounting literature.

    From the 10-Q filed 5 August 2026, Part I, Item 4. Controls and Procedures. Read it in the filing

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

  • It isn't cheap on profits: 47.9× operating profit.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.