Codexis

CDXS on Nasdaq. Codexis sells enzymes and manufacturing tools to drugmakers. Market value $152m.

Watch this stockFree. We tell you when something changes.

Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

Should I look at this?

Not a fit for our list right now

See Materials stocks that passed both tests

This is not advice. Check the numbers below.

Compare with another stock

Cash yield
past 12 months to June 2026
-8.2%low

For every $100 of what the whole company costs, it produced $-8.18 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
-82.8%five-year median

Each dollar kept in the business earns -83 cents a year. Above 10 is good.

Quality score: 25 of 100. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$1.36 a share, 42% above its 1-year low

Over the past year the price has ranged from $0.96 to $2.98.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.0
0.0
-0.1
-0.1
-0.0
-0.0
2021202220232024202512 monthsto Jun '26

Spare cash swings from quarter to quarter here: a shortfall of $12 million in the past 12 months, a shortfall of $24 million in the year to December 2025.

Revenue
$105m$139m$70m$59m$70m
Operating margin
-21.7%-25.2%-97.0%-98.6%-59.3%
Debt to equity
n/an/a0.000.430.79
Shares outstanding
0.07bn0.07bn0.08bn0.09bn0.11bn

Health checks

  • Free cash flow positive1 of 5 years
  • Accounting checksSkipped: company is not yet profitable
  • Debt0.79× equity
  • Revenue growth, five yearsSlow, 0.4% a year
  • Buying back its own sharesNo, 67% more shares since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • Sales: $15 million last quarter, about the same as a year ago.
  • A loss of $12 million, compared with a loss of $13 million a year ago.
  • It loses 36 cents on each $1 of sales, compared with 100 cents a year earlier.
  • Over the past 12 months it spent $12 million more cash than it brought in, compared with $68 million a year earlier.
  • 7% more shares than a year ago. Each share owns a bit less of the company.
  • Debt is $14 million more than cash, up from $13 million a year ago.
  • Sales grew on a year ago in 2 of the last 4 quarters.
Sales by quarter
Sales by quarter
Quarter toAmount
September 2024$13m
December 2024$21m
March 2025$8m
June 2025$15m
September 2025$9m
December 2025$39m
March 2026$15m
June 2026$15m
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$21m
December 2024-$10m
March 2025-$21m
June 2025-$13m
September 2025-$20m
December 2025$10m
March 2026-$9m
June 2026-$12m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
11 March 2026
Next quarterly (estimated, 10-Q)
10 November 2026

Who owns it

2 long-term investors we follow own it, unchanged from 2 last quarter. 149 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

6 investors own more than 5%.

  • Opaleye Management Inc.
    Passive investor
    at least 7.5%−0.1 pts
    (filed with 2 related holders)
    Since 31 March 2026
  • Aberdeen Group plc
    Passive investor
    at least 7.4%−1.4 pts
    (filed with 1 related holder)
    Since 30 June 2026
  • at least 7.3%
    (filed with 2 related holders)
    Since 24 July 2026
  • BlackRock, Inc.
    Passive investor
    7.2%
    Since 31 March 2025
  • LYTTON LAURENCE W
    Passive investor
    5.2%+0.2 pts
    Since 30 June 2026
  • Integrated Core Strategies (US) LLC
    Passive investor
    at least 5.2%
    (filed with 3 related holders)
    Since 9 April 2026
  • FMR LLC
    Passive investor
    Sold down below 5%
    Since 30 September 2025
  • The Vanguard Group
    Passive investor
    Sold down below 5%
    Since 13 March 2026
  • CASDIN CAPITAL, LLC
    Passive investor
    Sold down below 5%
    Since 30 September 2025

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

No insider bought shares on the open market in the last 12 months. 5 sold $81,795.

  • De Vre Raymond
    Director
    Sold
    Date
    11 June 2026
    Shares
    2,605
    Price
    $2.37
    Value
    $6,174
  • Lutz Stefan
    Chief Scientific Officer
    Sold
    Date
    24 February 2026
    Shares
    5,862
    Price
    $1.13
    Value
    $6,624
  • Lutz Stefan
    Chief Scientific Officer
    Sold
    Date
    6 February 2026
    Shares
    2,492
    Price
    $1.31
    Value
    $3,265
  • Erbez Georgia
    See Remarks
    Sold
    Date
    6 February 2026
    Shares
    3,826
    Price
    $1.31
    Value
    $5,012
  • MOORE ALISON
    President and CEO, Director
    Sold
    Date
    6 February 2026
    Shares
    3,826
    Price
    $1.31
    Value
    $5,012
  • Lutz Stefan
    CSO
    Sold
    Date
    7 January 2026
    Shares
    4,685
    Price
    $1.70
    Value
    $7,965
  • WOLF DENNIS P
    Director
    Sold
    Date
    21 November 2025
    Shares
    8,952
    Price
    $1.56
    Value
    $13,965
  • De Vre Raymond
    Director
    Sold
    Date
    11 November 2025
    Shares
    1,413
    Price
    $1.74
    Value
    $2,459
  • MOORE ALISON
    Chief Technical Officer
    Sold
    Date
    13 October 2025
    Shares
    6,239
    Price
    $2.51
    Value
    $15,660
  • Erbez Georgia
    Chief Financial Officer
    Sold
    Date
    13 October 2025
    Shares
    6,239
    Price
    $2.51
    Value
    $15,660

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

None of the serious warning signs we check for were found. 1 thing worth knowing.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 11 Mar 2026, plus the 10-Q filed 11 Aug 2026 and 6 later 8-Ks.

  • One big customer

    Worth knowing

    One customer brings in a big share of sales: 51% last year. Losing that customer would hurt.

    “For the year ended December 31, 2025, one customer accounted for approximately 51% of our total revenues.”

    From the 10-K filed 11 March 2026, Item 1. Business. Read it in the filing

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

  • Sales have barely grown: 0.4% a year.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
Create a free account to run it

Your first deep dive is free.

What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.