Monte Rosa Therapeutics

GLUE on Nasdaq. Biological products, (no diagnostic substances). Market value $876m.

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Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

We can't read total debt from the filing, so debt is left out.

Should I look at this?

Not a fit for our list right now

See Health care stocks that passed both tests

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
-3.8%low

For every $100 of what the whole company costs, it produced $-3.81 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: not known. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$9.87 a share, 36% above its 1-year low

Over the past year the price has ranged from $7.24 to $25.77.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.1
-0.1
-0.1
0.0
-0.0
-0.0
2021202220232024202512 monthsto Jun '26
Revenue
n/an/a$0$76m$124m
Operating margin
n/an/an/a-107.3%-43.8%
Debt to equity
n/an/an/an/an/a
Shares outstanding
0.05bn0.05bn0.06bn0.07bn0.09bn

Health checks

  • Free cash flow positive1 of 5 years
  • Accounting checksSkipped: company is not yet profitable
  • DebtUnknown
  • Revenue growth, five yearsUnknown
  • Buying back its own sharesNo, 76% more shares since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • Sales: $9 million last quarter, down 61% on a year ago.
  • A loss of $43 million, compared with a loss of $12 million a year ago.
  • It loses 633 cents on each $1 of sales, after keeping 8 cents a year earlier.
  • Over the past 12 months it spent $32 million more cash than it brought in. A year earlier it had $24 million spare.
  • 23% more shares than a year ago. Each share owns a bit less of the company.
  • Sales grew on a year ago in 1 of the last 4 quarters.
Sales by quarter
Sales by quarter
Quarter toAmount
September 2024$9m
December 2024$61m
March 2025$85m
June 2025$23m
September 2025$13m
December 2025$3m
March 2026$4m
June 2026$9m
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$24m
December 2024$13m
March 2025$47m
June 2025-$12m
September 2025-$27m
December 2025-$46m
March 2026-$45m
June 2026-$43m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
17 March 2026
Next quarterly (estimated, 10-Q)
5 November 2026

Who owns it

None of the long-term investors we follow own it. 193 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

11 investors own more than 5%.

  • 10.5%+3.0 pts
    Since 30 June 2026
  • Baker Bros. Advisors LP
    Passive investor
    at least 10.0%+3.3 pts
    (filed with 3 related holders)
    Since 31 March 2026
  • Adam Goulburn
    Passive investor
    at least 8.1%−0.6 pts
    (filed with 8 related holders)
    Since 31 March 2026
  • New Enterprise Associates 17, L.P.
    Passive investor
    at least 7.9%−1.8 pts
    (filed with 11 related holders)
    Since 1 July 2026
    What they said

    The information provided in Item 5(c) is hereby incorporated by reference. Depending on market conditions and other factors, NEA 17 and the Reporting Persons may dispose of additional shares of the Issuer.

    Read the filing
  • BVF PARTNERS L P/IL
    Passive investor
    at least 6.3%+0.4 pts
    (filed with 9 related holders)
    Since 31 March 2026
  • BlackRock, Inc.
    Passive investor
    6.3%
    Since 31 December 2024
  • Chen Yu
    Passive investor
    at least 5.5%−1.7 pts
    (filed with 4 related holders)
    Since 31 March 2026
  • Vestal Point Capital, LP
    Passive investor
    at least 5.4%
    (filed with 1 related holder)
    Since 30 June 2026
  • Montanova Capital, LLC
    Passive investor
    at least 4.2%−1.3 pts
    (filed with 2 related holders)
    Since 30 June 2026
  • Versant Venture Capital VI, L.P.
    Passive investor
    at least 3.4%−1.7 pts
    (filed with 4 related holders)
    Since 7 January 2026
  • FMR LLC
    Passive investor
    at least 2.8%
    (filed with 1 related holder)
    Since 30 May 2025
  • The Vanguard Group
    Passive investor
    Sold down below 5%
    Since 30 September 2025
  • Sold down below 5%
    Since 30 September 2025

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

No insider bought shares on the open market in the last 12 months. 8 sold $4m, $2m of it under preset trading plans.

  • Bowen Matthew
    Principal Accounting Officer
    Sold
    Date
    5 October 2026
    Shares
    13
    Price
    $10.56
    Value
    $137
  • Warmuth Markus
    President & CEO, Director
    Sold
    Date
    16 July 2026
    Shares
    9,500
    Price
    $23.18
    Value
    $220,219
  • Champoux Jennifer
    Chief Operating Officer
    Sold
    under a preset trading plan
    Date
    15 July 2026
    Shares
    4,351
    Price
    $23.38
    Value
    $101,730
  • Townson Sharon
    Chief Scientific Officer
    Sold
    under a preset trading plan
    Date
    6 July 2026
    Shares
    6,000
    Price
    $23.31
    Value
    $139,849
  • Janku Filip
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    30 June 2026
    Shares
    5,407
    Price
    $24.50
    Value
    $132,472
  • Janku Filip
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    29 June 2026
    Shares
    6,000
    Price
    $22.95
    Value
    $137,700
  • Manning Anthony M.
    Director
    Sold
    Date
    29 June 2026
    Shares
    10,000
    Price
    $23.11
    Value
    $231,100
  • Janku Filip
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    24 June 2026
    Shares
    30,000
    Price
    $21.42
    Value
    $642,600
  • Janku Filip
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    23 June 2026
    Shares
    11,845
    Price
    $20.22
    Value
    $239,506
  • Townson Sharon
    Chief Scientific Officer
    Sold
    under a preset trading plan
    Date
    23 June 2026
    Shares
    3,000
    Price
    $20.00
    Value
    $60,000

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

None of the warning signs we check for were found.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 17 Mar 2026, plus the 10-Q filed 6 Aug 2026 and 5 later 8-Ks.

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

Cheap for a reason is the question the numbers cannot answer.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.