Grail

GRAL on Nasdaq. GRAIL sells a blood test for many cancers to doctors and employers. Market value $6.9bn.

Watch this stockFree. We tell you when something changes.

Price checks use the past 12 months to June 2026. Some use the latest annual report instead, as marked. Quality checks use five annual reports, the latest for the year to December 2025.

Capital spending looks too small to be complete, so we leave free cash flow out.

Should I look at this?

Not a fit for our list right now

See Health care stocks that passed both tests

This is not advice. Check the numbers below.

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Cash yield
annual report to December 2025
n/a

We could not compute this from the filings.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: not known. Price score: 16 of 100. Our list needs 70 on quality and 60 on price.

$137.28 a share, 231% above its 1-year low

Over the past year the price has ranged from $41.50 to $166.48.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.6
n/a
20242025
Revenue
$126m$147m
Operating margin
-1743.0%-382.0%
Debt to equity
0.000.00
Shares outstanding
0.04bn0.04bn

Health checks

  • Free cash flow positive0 of 1 years
  • Accounting looks honest (Beneish)Not enough data
  • Financial strength (Piotroski)3 of 7 checks we could run
  • Profit backed by cash (accruals)Yes
  • Debt0.00× equity
  • Revenue growth, five yearsUnknown
  • Buying back its own sharesNo, 15% more shares since 2024

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • Sales: $45 million last quarter, up 26% on a year ago.
  • A loss of $110 million, compared with a loss of $114 million a year ago.
  • It loses 338 cents on each $1 of sales, compared with 471 cents a year earlier.
  • 20% more shares than a year ago. Each share owns a bit less of the company.
  • It has $56 million more cash than debt, down from $127 million a year ago.
  • Sales grew on a year ago in each of the last 4 quarters.
Sales by quarter
Sales by quarter
Quarter toAmount
September 2024$29m
December 2024$38m
March 2025$32m
June 2025$36m
September 2025$36m
December 2025$44m
March 2026$41m
June 2026$45m
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$126m
December 2024-$97m
March 2025-$106m
June 2025-$114m
September 2025-$89m
December 2025-$99m
March 2026-$93m
June 2026-$110m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
12 March 2026
Next quarterly (estimated, 10-Q)
5 November 2026

Who owns it

2 long-term investors we follow own it, unchanged from 2 last quarter. 373 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

7 investors own more than 5%.

  • Baker Bros. Advisors LP
    Passive investor
    at least 9.8%+4.5 pts
    (filed with 3 related holders)
    Since 31 March 2026
  • at least 9.6%+1.8 pts
    (filed with 28 related holders)
    Since 30 June 2026
  • BlackRock, Inc.
    Passive investor
    7.9%+1.4 pts
    Since 30 June 2026
  • STATE STREET CORPORATION
    Passive investor
    5.6%
    Since 30 June 2026
  • 5.1%+0.4 pts
    Since 30 June 2026
  • CRCM LLC
    Passive investor
    at least 5.0%−0.1 pts
    (filed with 7 related holders)
    Since 6 October 2025
  • Sessa Capital (Master), L.P.
    Passive investor
    at least 4.3%
    (filed with 4 related holders)
    Since 30 April 2025
  • Illumina, Inc.
    Passive investor
    Sold down below 5%
    Since 31 December 2025
  • Farallon Capital Partners, L.P.
    Passive investor
    Sold down below 5%
    Since 31 March 2026
  • The Vanguard Group
    Passive investor
    Sold down below 5%
    Since 13 March 2026
  • Fried, Richard B
    Passive investor
    Sold down below 5%
    Since 31 December 2025

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

No insider bought shares on the open market in the last 12 months. 4 sold $32m, $9m of it under preset trading plans.

  • Freidin Aaron
    Chief Financial Officer
    Sold
    under a preset trading plan
    Date
    21 September 2026
    Shares
    4,100
    Price
    $93.34
    Value
    $382,679
  • Ofman Joshua J.
    Chief Executive Officer, Director
    Sold
    under a preset trading plan
    Date
    21 September 2026
    Shares
    61,452
    Price
    $97.74
    Value
    $6m
  • Ofman Joshua J.
    Chief Executive Officer, Director
    Sold
    under a preset trading plan
    Date
    27 August 2026
    Shares
    5,000
    Price
    $85.02
    Value
    $425,098
  • Freidin Aaron
    Chief Financial Officer
    Sold
    under a preset trading plan
    Date
    27 August 2026
    Shares
    7,900
    Price
    $85.01
    Value
    $671,579
  • Partridge Andrew John
    Chief Growth Officer
    Sold
    Date
    4 June 2026
    Shares
    1,491
    Price
    $61.08
    Value
    $91,070
  • Freidin Aaron
    Chief Financial Officer
    Sold
    Date
    8 April 2026
    Shares
    45,806
    Price
    $49.92
    Value
    $2m
  • RAGUSA ROBERT P
    Chief Executive Officer, Director
    Sold
    Date
    8 April 2026
    Shares
    123,502
    Price
    $49.92
    Value
    $6m
  • Ofman Joshua J.
    President, Director
    Sold
    Date
    8 April 2026
    Shares
    61,665
    Price
    $49.92
    Value
    $3m
  • Freidin Aaron
    Chief Financial Officer
    Sold
    Date
    9 March 2026
    Shares
    2,492
    Price
    $47.89
    Value
    $119,340
  • Ofman Joshua J.
    President
    Sold
    Date
    9 March 2026
    Shares
    2,937
    Price
    $47.89
    Value
    $140,650

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

None of the warning signs we check for were found.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 12 Mar 2026, plus the 10-Q filed 6 Aug 2026 and 4 later 8-Ks.

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

Cheap for a reason is the question the numbers cannot answer.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.