Cartesian Therapeutics

RNAC on Nasdaq. Cartesian Therapeutics sells cell therapies that treat autoimmune diseases to patients. Market value $216m.

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Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

We can't read total debt from the filing, so debt is left out.

Should I look at this?

Not a fit for our list right now

See Health care stocks that passed both tests

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
-36.4%low

For every $100 of what the whole company costs, it produced $-36.39 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: 10 of 100. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$7.14 a share, 27% above its 1-year low

Over the past year the price has ranged from $5.60 to $11.00.

Pays no dividend

Prices from Monday’s close (5 October).

Five years of cash, in billions

-0.1
-0.0
-0.1
-0.0
-0.1
-0.1
2021202220232024202512 monthsto Jun '26
Revenue
$85m$111m$26m$39m$3m
Operating margin
-5.4%13.1%-332.3%-112.8%-5127.1%
Debt to equity
n/an/an/an/an/a
Shares outstanding
0.15bn0.16bn0.03bn0.03bn0.03bn

Health checks

  • Free cash flow positive0 of 5 years
  • Accounting checksSkipped: company is not yet profitable
  • DebtUnknown
  • Revenue growth, five yearsShrinking, 30.0% a year
  • Buying back its own sharesYes, 80% fewer since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • Sales: $0 last quarter, down 100% on a year ago.
  • Profit: $16 million, about the same as a year ago.
  • It loses 10519 cents on each $1 of sales, compared with 8578 cents a year earlier.
  • Over the past 12 months it spent $79 million more cash than it brought in, compared with $45 million a year earlier.
  • 13% more shares than a year ago. Each share owns a bit less of the company.
  • Sales grew on a year ago in 2 of the last 4 quarters.
Sales by quarter
Sales by quarter
Quarter toAmount
September 2024$387,000
December 2024-$759,000
March 2025$1m
June 2025$298,000
September 2025$452,000
December 2025$947,000
March 2026$78,000
June 2026$0
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$24m
December 2024-$10m
March 2025-$18m
June 2025$16m
September 2025-$36m
December 2025-$93m
March 2026-$39m
June 2026$16m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
9 March 2026
Next quarterly (estimated, 10-Q)
5 November 2026

Who owns it

None of the long-term investors we follow own it. 95 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

5 investors own more than 5%.

  • Timothy A. Springer
    Insider or founder
    at least 36.9%+0.1 pts
    (filed with 2 related holders)
    Since 13 January 2025
    What they said

    N/A

    Read the filing
  • Murat Kalayoglu
    Insider or founder
    at least 19.9%
    (filed with 3 related holders)
    Since 31 March 2026
    What they said

    Item 4 of the Schedule 13D is supplemented as follows: On March 31, 2026, Murat Kalayoglu resigned as a member of the Issuer's board of directors. On April 2, 2026, pursuant to a Notice of Optional Conversion delivered to the Issuer by the Trust pursuant to Section 6.02 of the…

    Read the filing
  • Squarepoint Ops LLC
    Passive investor
    at least 8.3%
    (filed with 5 related holders)
    Since 9 March 2026
  • Barclays PLC
    Passive investor
    6.0%
    Since 30 June 2026
  • FMR LLC
    Passive investor
    at least 3.0%−2.3 pts
    (filed with 1 related holder)
    Since 31 March 2026
  • JPMORGAN CHASE & CO.
    Passive investor
    Sold down below 5%
    Since 30 June 2026

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

In the last 12 months, 1 insider bought $205,800 of shares on the open market. 3 sold $258,683.

  • Brunn Carsten
    President and CEO, Director
    Sold
    Date
    6 January 2026
    Shares
    23,766
    Price
    $6.82
    Value
    $162,084
  • Miljkovic Milos
    Chief Medical Officer
    Sold
    Date
    6 January 2026
    Shares
    3,573
    Price
    $6.82
    Value
    $24,368
  • Davis Blaine
    Chief Financial Officer
    Sold
    Date
    6 January 2026
    Shares
    10,591
    Price
    $6.82
    Value
    $72,231
  • BARABE TIMOTHY C
    Director
    Bought
    Date
    4 December 2025
    Shares
    30,000
    Price
    $6.86
    Value
    $205,800

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

None of the warning signs we check for were found.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 9 Mar 2026, plus the 10-Q filed 6 Aug 2026 and 7 later 8-Ks.

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

  • Sales have shrunk: 30.0% a year.
  • It owes more than it owns on paper (negative equity). Often that's from borrowing to buy back shares.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.