Revolution Medicines

RVMD on Nasdaq. Revolution Medicines develops cancer medicines and sells them to patients and doctors. Market value $44.5bn.

Watch this stockFree. We tell you when something changes.

Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

We can't read total debt from the filing, so debt is left out.

Should I look at this?

Not a fit for our list right now

See Health care stocks that passed both tests

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
-2.9%low

For every $100 of what the whole company costs, it produced $-2.88 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: not known. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$199.87 a share, 336% above its 1-year low

Over the past year the price has ranged from $45.80 to $224.31.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.2
-0.2
-0.4
-0.6
-0.9
-1.2
2021202220232024202512 monthsto Jun '26
Revenue
$29m$35m$12m$0$0
Operating margin
-639.7%-730.0%-4207.1%n/an/a
Debt to equity
n/an/an/an/an/a
Shares outstanding
0.09bn0.11bn0.17bn0.19bn0.21bn

Health checks

  • Free cash flow positive0 of 5 years
  • Accounting looks honest (Beneish)Not enough data
  • Financial strength (Piotroski)1 of 7 checks we could run
  • Profit backed by cash (accruals)Yes
  • DebtUnknown
  • Revenue growth, five yearsUnknown
  • Buying back its own sharesNo, 141% more shares since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • A loss of $644 million, compared with a loss of $248 million a year ago.
  • Over the past 12 months it spent $1.2 billion more cash than it brought in, compared with $700 million a year earlier.
  • 12% more shares than a year ago. Each share owns a bit less of the company.
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$156m
December 2024-$195m
March 2025-$213m
June 2025-$248m
September 2025-$305m
December 2025-$365m
March 2026-$454m
June 2026-$644m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
25 February 2026
Next quarterly (estimated, 10-Q)
4 November 2026

Who owns it

2 long-term investors we follow own it, unchanged from 2 last quarter. 690 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

7 investors own more than 5%.

  • at least 6.4%−1.1 pts
    (filed with 28 related holders)
    Since 30 June 2026
  • BlackRock, Inc.
    Passive investor
    5.7%+1.2 pts
    Since 30 June 2026
  • Baker Bros. Advisors LP
    Passive investor
    at least 5.3%+0.4 pts
    (filed with 3 related holders)
    Since 30 June 2026
  • Wellington Management Company LLP
    Passive investor
    5.2%
    Since 30 June 2025
  • 5.1%+0.2 pts
    Since 30 June 2026
  • FMR LLC
    Passive investor
    at least 5.0%
    (filed with 1 related holder)
    Since 30 September 2025
  • at least 3.6%−1.9 pts
    (filed with 2 related holders)
    Since 31 December 2025
  • Farallon Capital Partners, L.P.
    Passive investor
    Sold down below 5%
    Since 31 December 2025
  • The Vanguard Group
    Passive investor
    Sold down below 5%
    Since 13 March 2026

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

No insider bought shares on the open market in the last 12 months. 12 sold $157m, $156m of it under preset trading plans.

  • Sandler Alan B.
    Chief Development Officer
    Sold
    under a preset trading plan
    Date
    29 September 2026
    Shares
    6,309
    Price
    $202.14
    Value
    $1m
  • Cislini Jeff
    SVP & General Counsel
    Sold
    under a preset trading plan
    Date
    25 September 2026
    Shares
    765
    Price
    $207.32
    Value
    $158,600
  • Mancini Anthony
    See Remarks
    Sold
    under a preset trading plan
    Date
    25 September 2026
    Shares
    3,121
    Price
    $200.54
    Value
    $625,885
  • Mancini Anthony
    See Remarks
    Sold
    under a preset trading plan
    Date
    24 September 2026
    Shares
    587
    Price
    $200.00
    Value
    $117,400
  • ANDERSON ELIZABETH M
    Director
    Sold
    under a preset trading plan
    Date
    22 September 2026
    Shares
    10,143
    Price
    $193.04
    Value
    $2m
  • Mancini Anthony
    See Remarks
    Sold
    under a preset trading plan
    Date
    18 September 2026
    Shares
    1,764
    Price
    $196.94
    Value
    $347,402
  • Mancini Anthony
    See Remarks
    Sold
    under a preset trading plan
    Date
    16 September 2026
    Shares
    1,774
    Price
    $199.24
    Value
    $353,449
  • Cislini Jeff
    SVP & General Counsel
    Sold
    under a preset trading plan
    Date
    16 September 2026
    Shares
    3,366
    Price
    $199.24
    Value
    $670,631
  • Sandler Alan B.
    Chief Development Officer
    Sold
    under a preset trading plan
    Date
    16 September 2026
    Shares
    341
    Price
    $199.24
    Value
    $67,941
  • Anders Jack
    Chief Financial Officer
    Sold
    under a preset trading plan
    Date
    16 September 2026
    Shares
    4,053
    Price
    $199.24
    Value
    $807,513

From Form 4 filings: insiders must report trades in their own company's shares within two days.

What could go wrong

Cheap for a reason is the question the numbers cannot answer.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.