Summit Therapeutics

SMMT on Nasdaq. Summit Therapeutics sells cancer drugs to patients. Market value $13.8bn.

Watch this stockFree. We tell you when something changes.

Price checks use the past 12 months to June 2026. Some use the latest annual report instead, as marked. Quality checks use five annual reports, the latest for the year to December 2025.

We can't read total debt from the filing, so debt is left out.

The company doesn't report operating profit, so we work it out from pre-tax profit and interest.

Should I look at this?

Look carefully before going further

Read the warning sign in its own filings

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
-3.3%low

For every $100 of what the whole company costs, it produced $-3.33 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
annual report to December 2025
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
n/a

The filings do not give us enough to work this out.

Quality score: not known. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$17.31 a share, 43% above its 1-year low

Over the past year the price has ranged from $12.07 to $29.23.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.1
-0.0
-0.1
-0.1
-0.3
-0.5
2021202220232024202512 monthsto Jun '26
Revenue
$2m$705,000$0$0n/a
Operating margin
-4764.3%-10225.4%n/an/an/a
Debt to equity
n/an/an/an/an/a
Shares outstanding
0.10bn0.70bn0.74bn0.74bn0.80bn

Health checks

  • Free cash flow positive0 of 5 years
  • Accounting looks honest (Beneish)Not enough data
  • Financial strength (Piotroski)Not enough data
  • Profit backed by cash (accruals)No
  • DebtUnknown
  • Revenue growth, five yearsUnknown
  • Buying back its own sharesNo, 713% more shares since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • A loss of $216 million, compared with a loss of $566 million a year ago.
  • Over the past 12 months it spent $460 million more cash than it brought in, compared with $207 million a year earlier.
  • 5% more shares than a year ago. Each share owns a bit less of the company.
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$56m
December 2024-$61m
March 2025-$63m
June 2025-$566m
September 2025-$232m
December 2025-$219m
March 2026-$189m
June 2026-$216m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
23 February 2026
Next quarterly (estimated, 10-Q)
22 October 2026

Who owns it

1 long-term investor we follow owns it, unchanged from 1 last quarter. 242 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

No one has reported a stake above 5% since December 2024.

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

In the last 12 months, 4 insiders bought $115m of shares on the open market.

  • Zanganeh Mahkam
    Co-Chief Executive Officer, Director
    Bought
    Date
    12 June 2026
    Shares
    3,810,000
    Price
    $13.12
    Value
    $50m
  • DUGGAN ROBERT W
    Co-Chief Executive Officer, Director
    Bought
    Date
    12 June 2026
    Shares
    3,810,000
    Price
    $13.12
    Value
    $50m
  • Soni Manmeet Singh
    COO and CFO, Director
    Bought
    Date
    4 June 2026
    Shares
    50,000
    Price
    $14.45
    Value
    $722,250
  • Zanganeh Mahkam
    Co-Chief Executive Officer, Director
    Bought
    Date
    4 June 2026
    Shares
    100,000
    Price
    $14.60
    Value
    $1m
  • DUGGAN ROBERT W
    Co-Chief Executive Officer, Director
    Bought
    Date
    4 June 2026
    Shares
    100,000
    Price
    $14.60
    Value
    $1m
  • Xia Yu
    Director
    Bought
    Date
    21 October 2025
    Shares
    533,617
    Price
    $18.74
    Value
    $10m
  • Zanganeh Mahkam
    Co-Chief Executive Officer, Director
    Bought
    Date
    21 October 2025
    Shares
    26,680
    Price
    $18.74
    Value
    $499,983
  • DUGGAN ROBERT W
    Co-Chief Executive Officer, Director
    Bought
    Date
    21 October 2025
    Shares
    26,680
    Price
    $18.74
    Value
    $499,983

From Form 4 filings: insiders must report trades in their own company's shares within two days.

Warning signs in its filings

Problems the company itself reported to the SEC, in its own words.

1 serious warning sign in Summit Therapeutics’ filings.

We look for five warning signs: doubt it can keep going, weak checks on its own accounts, a notice that its past accounts can't be relied on, a change of auditor, and one customer bringing in a big share of sales. We don't check lawsuits, investigations or debt yet.

We checked the auditor's report, internal controls, restatement notices, auditor changes and big customers in the 10-K filed 23 Feb 2026, plus the 10-Q filed 23 Jul 2026 and 14 later 8-Ks.

  • Doubt it can keep going

    Serious

    The company or its auditor warned it may not have enough money to last the next year.

    “These conditions raise substantial doubt about the Company’s ability to continue as a going concern.”
    Show the full paragraph
    Until the Company can generate substantial revenue and achieve profitability, the Company will need to raise additional capital to fund its ongoing operations and capital needs. The Company continues to evaluate options to further finance its operating cash needs for its product candidates through a combination of some, or all, of the following: equity and debt offerings, collaborations, strategic alliances, grants and clinical trial support from government entities, philanthropic, non-government and not-for-profit organizations, and marketing, distribution or licensing arrangements. There is no assurance, however, that additional financing will be available when needed or that management of the Company will be able to obtain financing on terms acceptable to the Company. If the Company is unable to obtain funding when required in the future, the Company could be required to delay, reduce, or eliminate research and development programs, product portfolio expansion, or future commercialization efforts, which could adversely affect its business prospects. These conditions raise substantial doubt about the Company’s ability to continue as a going concern.

    From the 10-Q filed 23 July 2026, Part I, Item 1. Financial Statements. Read it in the filing

A 10-K is the yearly report every US company files with the SEC. An 8-K is a short notice of a big event.

What could go wrong

Cheap for a reason is the question the numbers cannot answer.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.