Shattuck Labs

STTK on Nasdaq. Shattuck Labs develops antibody medicines for patients with inflammatory and immune diseases. Market value $652m.

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Price checks use the past 12 months to June 2026. Quality checks use five annual reports, the latest for the year to December 2025.

Should I look at this?

Not a fit for our list right now

See Health care stocks that passed both tests

This is not advice. Check the numbers below.

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Cash yield
past 12 months to June 2026
-7.0%low

For every $100 of what the whole company costs, it produced $-7.01 of spare cash in the past 12 months. A savings account pays about $4.

Price to profit
past 12 months to June 2026
n/a

The filings do not give us enough to work this out.

Return on capital
five annual reports to December 2025
-144.3%five-year median

Each dollar kept in the business earns -144 cents a year. Above 10 is good.

Quality score: 20 of 100. Price score: 0 of 100. Our list needs 70 on quality and 60 on price.

$5.86 a share, 245% above its 1-year low

Over the past year the price has ranged from $1.70 to $8.33.

Pays no dividend

Prices from Tuesday’s close (6 October).

Five years of cash, in billions

-0.1
-0.1
-0.1
-0.1
-0.0
-0.0
2021202220232024202512 monthsto Jun '26
Revenue
$30m$652,000$2m$6m$1m
Operating margin
-150.8%-15848.0%-5549.6%-1408.3%-5150.8%
Debt to equity
0.000.000.000.000.00
Shares outstanding
0.04bn0.04bn0.05bn0.06bn0.10bn

Health checks

  • Free cash flow positive0 of 5 years
  • Accounting checksSkipped: company is not yet profitable
  • Debt0.00× equity
  • Revenue growth, five yearsShrinking, 36.8% a year
  • Buying back its own sharesNo, 137% more shares since 2021

The quarter to June 2026

How the business did, compared with the same quarter a year earlier.

  • A loss of $15 million, compared with a loss of $12 million a year ago.
  • It loses 5579 cents on each $1 of sales, compared with 2168 cents a year earlier.
  • Over the past 12 months it spent $41 million more cash than it brought in, compared with $56 million a year earlier.
  • 154% more shares than a year ago. Each share owns a bit less of the company.
  • It has $63 million more cash than debt, up from $50 million a year ago.
  • Sales did not grow on a year ago in any of the last 4 quarters.
Sales by quarter
Sales by quarter
Quarter toAmount
September 2024$3m
December 2024$0
March 2025$0
June 2025$0
September 2025$1m
December 2025$0
March 2026$0
June 2026$0
Profit by quarter
Profit by quarter
Quarter toAmount
September 2024-$17m
December 2024-$19m
March 2025-$14m
June 2025-$12m
September 2025-$10m
December 2025-$13m
March 2026-$15m
June 2026-$15m

From the company's quarterly reports to the SEC.

Dates

Next results (estimated)
n/a
Last annual report (10-K)
5 March 2026
Next quarterly (estimated, 10-Q)
10 November 2026

Who owns it

None of the long-term investors we follow own it. 100 funds in all.

Jun '25
Dec '25
Jun '26
Largest holders overall

From 13F filings for the quarter ended 30 June 2026.

Big holders and activists

6 investors own more than 5%.

  • 15.3%+1.5 pts
    Since 30 June 2026
  • ORBIMED ADVISORS LLC
    Passive investor
    at least 10.0%0.0 pts
    (filed with 2 related holders)
    Since 11 June 2026
    What they said

    The Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in…

    Read the filing
  • Redmile Group, LLC
    Insider or founder
    at least 9.9%0.0 pts
    (filed with 2 related holders)
    Since 15 July 2026
  • Prosight Management, LP
    Passive investor
    at least 9.9%
    (filed with 4 related holders)
    Since 30 September 2025
  • Adage Capital Management, L.P.
    Passive investor
    at least 9.8%
    (filed with 3 related holders)
    Since 31 December 2024
  • Deep Track Capital, LP
    Passive investor
    at least 5.2%
    (filed with 2 related holders)
    Since 10 June 2026
  • The Vanguard Group
    Passive investor
    Sold down below 5%
    Since 30 June 2025
  • BlackRock, Inc.
    Passive investor
    Sold down below 5%
    Since 30 June 2025

From Schedule 13D and 13G filings: anyone owning more than 5% must file one.

What insiders did

In the last 12 months, 1 insider bought $250,000 of shares on the open market. 2 sold $591,850, $591,850 of it under preset trading plans.

  • Shukla Abhinav A.
    Chief Technical Officer
    Sold
    under a preset trading plan
    Date
    2 July 2026
    Shares
    410
    Price
    $7.01
    Value
    $2,874
  • Shukla Abhinav A.
    Chief Technical Officer
    Sold
    under a preset trading plan
    Date
    1 July 2026
    Shares
    100
    Price
    $7.07
    Value
    $707
  • Shukla Abhinav A.
    Chief Technical Officer
    Sold
    under a preset trading plan
    Date
    30 June 2026
    Shares
    23,365
    Price
    $7.08
    Value
    $165,424
  • Pandite Arundathy N.
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    30 June 2026
    Shares
    30,000
    Price
    $7.01
    Value
    $210,300
  • SIEGALL CLAY B
    Director
    Bought
    Date
    9 June 2026
    Shares
    62,500
    Price
    $4.00
    Value
    $250,000
  • Shukla Abhinav A.
    Chief Technical Officer
    Sold
    under a preset trading plan
    Date
    12 May 2026
    Shares
    2,032
    Price
    $7.01
    Value
    $14,244
  • Pandite Arundathy N.
    Chief Medical Officer
    Sold
    under a preset trading plan
    Date
    12 May 2026
    Shares
    30,000
    Price
    $6.61
    Value
    $198,300

From Form 4 filings: insiders must report trades in their own company's shares within two days.

What could go wrong

  • Sales have shrunk: 36.8% a year.

Whether the price already reflects the risks is what the deep dive is for.

The deep dive

Everything above is arithmetic on public filings. The deep dive reads the last ten years of annual reports, the proxy statements, and the earnings calls, then argues the case the way Buffett, Klarman, and Hohn would, and checks every claim against the source.

  • What the business is worth, as a range, and the margin of safety at today’s price
  • Prices to start buying, buy, and buy hard
  • The three things that would make this a mistake
  • Every number footnoted to the filing it came from
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What a finished deep dive looks like

Not advice. Numbers on this page come from SEC filings and are updated each night; prices are updated again after the US market closes. The five-year figures are rounded.